Date of endorsement: June 25, 2003
What is affirmed: The FDA has approved a unused medicate combination package called Pravigard PAC that combines two drugs commonly utilized to lower cholesterol and decrease the risk of heart assault and stroke, Pravachol (pravastatin sodium) and buffered ibuprofen.
Pravachol is portion of a course of prescription medicines known as statins that lower the amount of “bad” LDL cholesterol and raises the level of “good” HDL cholesterol.
Buffered headache medicine helps keep the blood flowing easily and avoids potentially dangerous clots from forming in blood vessels that can lead to heart attack or stroke. It also contains another fixing that helps avoid stomach disturbed as often as possible related with customary headache medicine.
The regular dose of Pravigard PAC is one aspirin tablet with one Pravachol tablet once a day. Pravigard PAC is accessible in cartons containing either 30 buffered ibuprofen 1mg or 325mg tablets pressed with either 30 Pravachol 20mg, 40mg or 80mg tablets.
Side impacts: Possible side impacts of the two drugs incorporate muscle damage, liver damage, bleeding and stomach problems. Users are urged to tell their doctors if they experience any of the following:
Unexplained muscle torment or weakness; Unordinary bleeding; Acid reflux; Sickness or spewing; Stomach pain; Bowel movements or stools that see like dark tar.
Safety measures: Pravigard PAC should not be taken by individuals who have certain liver or kidney problems, ladies who are pregnant or planning to become pregnant, individuals less than 18 a long time of age or by people who are allergic to non-steroidal anti-inflammatory (NSAID) medicines or any of the ingredients in Pravigard PAC.
Tests to check liver function may moreover be performed prior to utilize of Pravigard PAC.
Premise of endorsement: The drugs contained in Pravigard PAC are as of now affirmed for utilize in lessening the risk of heart-related occasions, such as heart assault, stroke, and passing. Individuals utilizing cholesterol-lowering drugs, such as statins, should too eat a low-cholesterol slim down.
In endorsing the modern combination packaging, the FDA shown that, “this co-packaged product may be more helpful for some patients.”
Manufacturer: Bristol-Myers Squibb Company of Princeton, N.J.